Engineering Journal: Science and InnovationELECTRONIC SCIENCE AND ENGINEERING PUBLICATION
Certificate of Registration Media number Эл #ФС77-53688 of 17 April 2013. ISSN 2308-6033. DOI 10.18698/2308-6033
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Article

Analysis of in dicators of body’s gas exchange in high-altitude flight based on a static model of the respiratory system

Published: 15.01.2021

Authors: Matyushev T.V., Dvornikov M.V., Ryzhenkov S.P., Petrov M.A.

Published in issue: #1(109)/2021

DOI: 10.18698/2308-6033-2021-1-2045

Category: Mechanics | Chapter: Biomechanics and Bioengineering

The purpose of the research was to analyze the dynamics of indicators of human gas exchange in high-altitude flight on the basis of a static model of the respiratory system of the body. First, we developed the structure of this model and an algorithm for calculating the gas exchange of the body. Next, we analyzed changes in indicators of the function of external respiration and gas exchange, and clarified the quantitative parameters that determine the nature of the relationships between the components of gas exchange. Finally, we carried out a computational experiment to simulate ascent to a height. The results of the analysis of the calculations showed that when a person rises to a height with a drop in pressure, tidal volumes change the volume of the alveolar space decreases and the dead space increases in the ratio from 4.7 to 0.7. An uncompensated respiratory alkalosis develops, leading to a violation of the acid-base reactions of the body.


References
[1] Isaev L.K., ed. Vozdeystvie na organizm cheloveka opasnykh i vrednykh ekologicheskikh faktorov. Metrologicheskie aspekty [The impact on the human body of hazardous and harmful environmental factors. Metrological aspects]. In 2 vols. Vol. II. Moscow, PAIMS Publ., 1997, 496 p.
[2] Grippi M.A. Pulmonary Pathophysiology. Lippincott Williams & Wilkins, 1st ed., 1995, 352 p. [In Russ.: Grippi M.A. Patofiziologiya legkikh. 2nd ed., rev. Moscow, St. Petersburg, ZAO Izd. BINOM, Nevskiy Dialekt Publ., 1999, 344 p.].
[3] Koenchi E.B. Dekompressionnye yavleniya na iskusstvennykh sputnikakh s zhivymi suschestvami na bortu. Chelovek v usloviyakh vysotnogo kosmicheskogo poleta. Sbornik perevodov iz inostrannoy periodicheskoy literatury [Decompression phenomena on artificial satellites with living things on board. Man in high-altitude space flight. Collection of translations from foreign periodical literature]. Ivanov V.I., ed. Moscow, In. lit. Publ., 1960, pp. 349–416. (In Russ.).
[4] Agadzhanyan N.A., Polunin I.N., Stepanov V.K., Polyakov V.N. Chelovek v usloviyakh gipokapnii i giperkapnii [Man in conditions of hypocapnia and hypercapnia]. Astrakhan, Moscow, Astrakhan. gos. med. akad. Publ., 2001, 340 p.
[5] Matyushev T.V., Dvornikov M.V., Ryzhenkov S.P., Guskov S.G., Dvorni-kov S.M. Aviakosmicheskaya i ekologicheskaya meditsina — Aerospace and Environmental Medicine, 2016, vol. 50, no. 5, pp. 144–145.
[6] Rudny I.M., Vasilev P.V., Gozulov S.A., ed. Aviatsionnaya meditsina: Rukovodstvo [Aviation medicine: a manual]. Moscow, Meditsina Publ., 1986, 580 p.
[7] Stepanov V.K. K voprosu ob opredelenii energotrat po nekotorym pokazatelyam fiziologicheskikh funktsiy [To the problem of determining energy consumption by some indicators of physiological functions]. In: Vliyanie faktorov vysotnogo poleta na organizm i metody izucheniya nekotorykh fiziologicheskikh funktsii [Influence of high-altitude flight factors on the body and methods of studying some physiological functions]. Moscow, VVS Publ., 1972, pp. 34–36.
[8] Matyushev T.V., Dvornikov M.V. Kompyuternye issledovaniya i modelirovanie — Computer Research and Modeling, 2017, vol. 9, no. 2, pp. 281–296.
[9] Schmidt R.F., Thews G., eds. Human Physiology. 2nd ed. Springer, 1989, 827 p. [In Russ.: Thews G. Transport gazov krovyu i kislotno-schelochnoe ravnovesie. Fiziologiya cheloveka. V 3 t., t. 2. 3rd ed. Moscow, Mir Publ., 2004, pp. 605–625].
[10] Fiziologiya dykhaniya. Rukovodstvo po fiziologii [Respiration physiology. Physiology manual]. L.L. Shik, et al., Editorial Board. Leningrad, Nauka Publ., Leningrad Dept., 1973, 352 p.